WormXpert

Intestinal helminthiasis remains one of the most prevalent and clinically underdiagnosed conditions in adult dogs. Adult dogs in high-exposure environments — including outdoor dogs, multi-pet households, dogs in contact with livestock and hunting breeds — face ongoing risk from both nematode and cestode infections throughout their lives.

Subclinical parasitism in adult dogs contributes to poor body condition, reduced nutrient utilisation, chronic gastrointestinal disturbance and significant zoonotic risk to human contacts — particularly children and immunocompromised individuals — through environmental faecal contamination with parasite eggs.

Each active component targets intestinal parasites via a distinct mechanism — providing complementary action across all major helminth classes:

*Echinococcus coverage is an important zoonotic consideration. Frequency of treatment in at-risk dogs should be guided by veterinary assessment of local epidemiology.

WormXpert is indicated for the treatment and prevention of mixed intestinal helminth infections in adult dogs in the following clinical scenarios:

• Routine scheduled deworming — of clinically healthy adult dogs at risk of intestinal parasitism
• Dogs with clinical signs of intestinal parasitism — weight loss, poor coat condition, chronic soft stool, scooting or visible proglottids
• High-exposure dogs — outdoor access, hunting breeds, farm dogs, dogs in contact with rodents or livestock
• Pre-vaccination deworming — to eliminate parasite-mediated immune suppression before vaccine administration
• Pre-breeding deworming — to reduce vertical transmission risk in bitches before mating
• Zoonotic risk reduction — in households with young children or immunocompromised individuals
• Shelter, boarding or multi-dog environments — where parasite load is elevated

• Pregnant or lactating bitches — use only on veterinary advice; safety data must be reviewed per component
• Concurrent anthelmintic therapy — avoid combining with other deworming agents without veterinary guidance
• Dogs on piperazine — pyrantel and piperazine have antagonistic mechanisms; do not co-administer
• MDR1/ABCB1 mutation (Collies and related breeds) — review safety profile of febantel metabolites under veterinary supervision before use

• Administer orally — tablets may be given directly or crushed and mixed into food
• Fasting is not required prior to administration
• For whipworm (Trichuris vulpis) — a 3-day treatment course or repeat dosing at 3 and 6 weeks may be advised by the veterinarian for heavy infections
• Store below 25°C in a cool, dry place, away from children

Clinical decisions should always be individualised by the treating veterinarian. References support the pharmacological and epidemiological basis of this formulation.

• 1 Bowman DD. Georgis' Parasitology for Veterinarians. 11th ed. Elsevier; 2021. Standard veterinary parasitology reference.
• 2 ESCCAP. Worm Control in Dogs and Cats. ESCCAP Guideline 01; 6th ed. 2021. Available at: esccap.org
• 3 Traversa D. Pet roundworms and hookworms: A continuing need for global worming. Parasites & Vectors. 2012;5:91. doi:10.1186/1756-3305-5-91 PMID: 22577965
• 4 Taylor MA, Coop RL, Wall RL. Veterinary Parasitology. 4th ed. Wiley-Blackwell; 2016. Anthelmintic mechanisms and parasite biology reference.
• 5 Dryden MW, Payne PA, Smith V. Treatment of Ancylostoma caninum, Uncinaria stenocephala and Trichuris vulpis infections in dogs. Vet Ther. 2007;8(4):224–232. PMID: 18183558
• 6 Montoya A, et al. Efficacy of a combination of praziquantel, pyrantel embonate and febantel against nematode and cestode infections in dogs. Parasitol Res. 1998;84(2):142-146. Provides specific clinical validation for the synergistic efficacy of the triple-active formulation found in WormXpert against a broad spectrum of intestinal parasites.